Proper mouse setup is crucial for any FPS game, especially as dynamic as quake. There are many discussions/studies in that matter:
http://www.excessiveplus.net/forums/thread/in-mouse-1-3-problem#comment-377203
http://www.esreality.com/post/1565939/quake3-exe-with-raw-mouse-input-support/
http://www.esreality.com/?a=post&id=1515298
How does mouse input implementation looks like in ioquake3 on Linux platform? Which in_mouse is best for lowest possible input lag? Does running DE (KDE4 in my case) have any impact on in-game mouse settings?
And yes, i have changed usb pooling rate.